Before the U.S. had a national highway system (courtesy of President ... His home is open for tours by appointment. Guthrie, Kentucky to East Ridge, Tennessee (195 miles) In Tennessee, US-41 follows ...

Several closures and restrictions will be in place along US-41 in western Kentucky as part of the Ohio River Crossing Project ...

Attention drivers in Henderson - several lane restrictions are starting Monday on US Highway 41.Officials say this is all for ...

According to the Madisonville Police Department (MPD), a chase started in Madisonville on I-69 and ended in Henderson.

A van caught fire following a crash with a pickup trailer at the intersection of US-41 and Evergreen Road in North Fort Myers ...

The California Highway Patrol says one person is dead following a three-car crash on Highway 41 in Madera County.

Highlighting talent from the eastern part of Kentucky, the U.S. 23 Country Music Highway Museum features 14 exhibits spanning country artists who have called the Bluegrass State home, including ...

U.S. Highway 163 is a 41-mile stretch that goes from Kayenta ... those wide-open prairies. Driving through Kentucky, turn onto the Lincoln Heritage National Scenic Highway for a dose of history ...

UPDATE: The crash that was blocking traffic on the ramp to I-275 from Dixie Highway has been cleared ... by Hearst's WLWT Alert Desk.Sharing brings us closer together. If this story happened ...

April 22 (UPI) --A minor shakeup in the Kentucky Derby lineup and some promising ... Woods 'honored' to play on required exemption at U.S. Open May 3 (UPI) -- Tiger Woods said he felt "honored ...

Resurfacing is expected to impact a large section of U.S. 41 on the north side of Terre Haute beginning next week. According to a release from INDOT, the portion of ...